

The amount of medicine that you take depends on the strength of the medicine. If your dose is different, do not change it unless your doctor tells you to do so. The following information includes only the average doses of this medicine. Follow your doctor's orders or the directions on the label. The dose of this medicine will be different for different patients. It is not safe to use more than 4 grams (4,000 milligrams) of acetaminophen in one day (24 hours).

Carefully check the labels of all other medicines you are using, because they may also contain acetaminophen. This combination medicine contains acetaminophen (Tylenol®). The average household teaspoon may not hold the right amount of liquid. Measure the oral liquid with a marked measuring spoon, oral syringe, dropper, or medicine cup. Ask your doctor if you have any questions. Read it again each time you refill your prescription in case there is new information. Read and follow these instructions carefully. This medicine should also come with a Medication Guide and patient information leaflet.

It is very important that you understand the rules of the Opioid Analgesic REMS program to prevent addiction, abuse, and misuse of hydrocodone and acetaminophen combination.
